A neck mass is never normal. Neck masses can result from a variety of causes. The most frequent cause of neck masses are from infection and cancer. Infections, particularly infections developing from teeth, can result in a neck mass. This usually requires surgical treatment. Cancer can also result in a neck mass. Cancer arising in the salivary glands or cancer that spreads from the head and neck to a lymph node in the neck can result in a neck mass. Neck masses can also result for a multitude or other reason such as thyroid lesions, developmental conditions, and blood vessel lesions. The approach to a neck mass involves a clinical exam supported by investigations such as CT scans and biopsies. If you or your doctor notice a neck mass, please make arrangements to see one of our Oral Cancer Institute surgeons for a comprehensive evaluation.